Results 171 to 180 of about 1,930,714 (341)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Parametric Life Cycle Assessment of Chemical Recycling of Nylon-6 to Caprolactam. [PDF]

open access: yesEnviron Sci Technol
Minor AJ   +5 more
europepmc   +1 more source

Life Cycle Assessment (LCA)

open access: green
McManus, Marcelle   +10 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Life Cycle Assessment of an Office Building in Finland Using a Custom Assessment Tool [PDF]

open access: gold
Hüseyin Emre Ilgın   +3 more
openalex   +1 more source

Quantification of Non-linearities in the Consequential Life Cycle Assessment of the Use Phase of Battery Electric Vehicles

open access: gold, 2021
Davide Rovelli   +6 more
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Turbine blade tip durability analysis [PDF]

open access: yes
An air-cooled turbine blade from an aircraft gas turbine engine chosen for its history of cracking was subjected to advanced analytical and life-prediction techniques.
Laflen, J. H.   +2 more
core   +1 more source

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