Results 191 to 200 of about 1,930,714 (341)

Sustainable Design: economic and environmental life cycle assessment model [PDF]

, 2009
Thiebat, Francesca
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Challenges, Innovations, and Future Directions in Life Cycle Assessment of Product and Process Impacts

BioResources
Reliable estimation of the environmental impacts of processes and products is essential for achieving the Sustainable Development Goals. Life cycle assessment (LCA) is a key method for evaluating such effects.
Nicolás Martín Clauser, Maria Cristina Area   +1 more
doaj  

An Efficient Screening Life Cycle Assessment Approach: Assessing the Environmental Impact of Dialysis Treatments. [PDF]

Adv Ther
Seemann K, Fernández-Barceló C, Makaryan S, Veith T, Boeger S, Kendzia D.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Novel green UPLC method with life cycle assessment for determination of favipiravir and molnupiravir drugs and environmental water samples. [PDF]

Sci Rep
Kelani KM, Elsherbiny MS, Eid SM, Ghany MFA, Abbas MM.   +4 more
europepmc   +1 more source

Needs assessment for predictable organization transitions : the case of the initial public offering (IPO) in the organization life cycle [PDF]

, 1992
Rob Dainow
openalex  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Life cycle assessment of electric and gasoline vehicles considering grid differences and cold climate in China. [PDF]

Sci Rep
Ma S, He Z, Sharaai AH, Matthew NK, Zainordin NS.   +4 more
europepmc   +1 more source

Attributional and consequential life cycle assessment of bioethanol-based PVC [PDF]

, 2012
De Meester, Steven, Dewulf, Jo, Freitas de Alvarenga, Rodrigo, Hruska, Zdenek, Martinz, Daniel, Thommeret, Richard, Van Langenhove, Herman, Villers, Joseph, Wathelet, Alain   +8 more
core   +1 more source