Results 191 to 200 of about 1,917,255 (320)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Challenges, Innovations, and Future Directions in Life Cycle Assessment of Product and Process Impacts

BioResources
Reliable estimation of the environmental impacts of processes and products is essential for achieving the Sustainable Development Goals. Life cycle assessment (LCA) is a key method for evaluating such effects.
Nicolás Martín Clauser, Maria Cristina Area   +1 more
doaj  

A more basic modeling framework for life cycle methods to cover non-linear, dynamic, and integrated effects–looking beyond linear inverse modeling

Frontiers in Sustainability, 2022
Thomas Schaubroeck
doaj   +1 more source

Life Cycle Assessment of Chemical Upcycling of Postconsumer Polyethylene Terephthalate to Kevlar Polymer. [PDF]

ACS Sustain Chem Eng
Han J, Nain P, Peterson RL, Neppel EP, Anctil A.   +4 more
europepmc   +1 more source

Energy circularity reduces environmental impacts in building-integrated agriculture (BIA): A life-cycle energy assessment

Joan Muñoz‐Liesa, Michael Martin, Anna Petit‐Boix, Xavier Gabarrell, Thomas Nemecek, Mélanie Douziech, Eva Cuerva, Santiago Gassó, Alejandro Josa   +8 more
openalex   +1 more source

Sustainable Design: economic and environmental life cycle assessment model [PDF]

, 2009
Thiebat, Francesca
core  

Harpacticoid copepods in risk assessment : combining life cycle experiments with population modeling [PDF]

, 2017
De Schamphelaere, Karel, Janssen, Colin, Koch, Josef   +2 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

BIM-integrated life cycle assessment of decentralized cement-based waste recycling in renovation projects. [PDF]

Sci Rep
Younes A, Elbeltagi E, Ehab A, Diab A, Hamdallah M, Abazeed A.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source