Results 231 to 240 of about 25,951,973 (349)
Disparities in hospice enrollment timing and end-of-life care intensity across non-cancer diagnoses: a 10-year hospital-based cohort study. [PDF]
Ann MedWang CL, Lee LC, Hsu CY, Lin CY.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
High life, low life and common life: The role of affections and love in citizenship [PDF]
, 2005 Kocan, Gurcan +3 more
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Family burden and happiness in mothers of children with intellectual and developmental disabilities: role of support and quality of life. [PDF]
BJPsych OpenSardohan Yildirim AE +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Association of life-course stressful life events with later-life intrinsic capacity: A multi-cohort study. [PDF]
J Nutr Health AgingZhou Y +4 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source