Results 121 to 130 of about 11,798,814 (348)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Flexible Working, Work–Life Balance, and Gender Equality: Introduction
Social Indicators Research, 2018 This special brings together innovative and multidisciplinary research (sociology, economics, and social work) using data from across Europe and the US to examine the potential flexible working has on the gender division of labour and workers’ work–life ...
Heejung Chung, Tanja van der Lippe
semanticscholar +1 more source
Tipping the balance: the problematic nature of work–life balance in a low-income neighbourhood. [PDF]
The article attempts to locate the contested notion of work–life balance within the context of global trends and recent policy developments. It describes a small-scale qualitative study of work–life balance as it is experienced within a low-income ...
Dean, Hartley
core +1 more source
Work-Life balance: towards an agenda for policy learning between Britain and Germany [PDF]
, 2002 This survey analyses the political context, the legislative frameworks and the policy developments in an area that is now widely termed 'work-life balance' in both the United Kingdom and Germany.
Arthur, Lore
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
New Zealand Medical Student JournalI have often pondered how to acquire the elusive ‘work-life balance’. Does such a balance exist? Is it as delicate as the whisper of a but- terfly’s wings? Or perhaps as ephemeral as the beauty of a cherry blossom tree?
Maple Goh
doaj +1 more source
, 2013 Considers the intersection between employment policy and family law, and the changes in work and family regarding traditional gender roles. Examines UK and EU policy initiatives aimed at achieving a better work/life balance for employees with children ...
Mair, Jane
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source