Results 141 to 150 of about 11,798,814 (348)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

WORK / LIFE BALANCE REFLECTIONS ON EMPLOYEE SATISFACTION [PDF]

open access: yesSerbian Journal of Management, 2011
The aim of this research is to analyze the relationship between employee satisfaction andwork/life balance. The construct used for this research consists of career opportunity, recognition,work tasks, payments, benefits, superior subordinate relationship,
Selvarani, Kamalanabhan, Sakthivel Rani
doaj  

Working parents and workplace flexibility in New Hampshire [PDF]

open access: yes, 2010
This report, a joint effort between the Carsey Institute, UNH Cooperative Extension, and New Hampshire Employment Security, looks at working parents and their job flexibility and the importance it has for families trying to achieve a work-life ...
Smith, Kristin, Smith, Malcolm
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Burnout and satisfaction with work-life balance among US physicians relative to the general US population.

open access: yesArchives of Internal Medicine, 2012
T. Shanafelt   +8 more
semanticscholar   +1 more source

PENGARUH KEPEMIMPINAN ISLAMI, WORK LIFE BALANCE DAN ORGANIZATIONAL CITIZENSHIP BEHAVIOR TERHADAP KINERJA KARYAWAN PADA BAZNAS LOMBOK TIMUR [PDF]

open access: yes
This research aims to determine the influence of Islamic leadership, work life balance, organizational citizenship behavior and employee performance at BAZNAS East Lombok.
Rizki, Nia Ihzayanti
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Work-life balance, management practices and productivity. [PDF]

open access: yes
Do “Anglo-Saxon” management practices generate higher productivity only at the expense of lousy work-life balance (WLB) for workers? Many critics of “neo-libéralisme sauvage” have argued that increased competition from globalisation is damaging employees’
Bloom, Nick   +2 more
core   +1 more source

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