Results 101 to 110 of about 2,952,860 (261)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Two Economists’ Musings on the Stability of Locus of Control [PDF]

open access: yes
Empirical studies of the role of non-cognitive skills in driving economic behavior often rely heavily on the assumption that these skills are stable over the relevant time frame. We analyze the change in a specific non-cognitive skill, i.e.
Cobb-Clark, Deborah A.   +1 more
core   +3 more sources

Does Education Cause Spiritual Belief Change?

open access: yesCurrent Issues in Education, 2012
Currently, little is known about the influence classroom learning has on the spiritual beliefs of students.  Despite this fact, decisions on educational policy, parental home schooling, and even whether to bring legal actions against school districts ...
Donald Thomas Markle
doaj  

Experiences of Healthcare Providers in Providing Care for Patients with COVID-19: A Qualitative Study

open access: yesIranian Journal of Nursing and Midwifery Research
Background: The COVID-19 pandemic put enormous pressure on healthcare providers and patients. Exploring the experiences of healthcare providers involved in this crisis can help prevent potential complications and manage similar crises in the future. This
Mojghan Janighorban   +2 more
doaj   +1 more source

Experiences of women in the care of their children diagnosed with severe and/or moderate symptomatic haemophilia

open access: yesIatreia, 2018
Objective: To describe the experiences of women in the care of their children diagnosed with severe and/or moderate symptomatic haemophilia who have received care at the Hematology Service of the Hospital de San José (HSJ), Bogotá, Colombia.
Casas, Claudia Patricia   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Histórias de perdas fetais contadas por mulheres: estudo de análise qualitativa

open access: yesRevista de Saúde Pública
OBJETIVO: (Re)conhecer o significado da perda fetal para mulheres que vivenciaram a experiência, a partir da compreensão do processo de gravidez, com base em seus relatos.
Alba Lúcia Dias dos Santos   +2 more
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Restructuring an Empire. A narrative study of the turnaround of the telecom company Ericsson. [PDF]

open access: yes
The turnaround of the telecom company Ericsson is considered a unique chapter in Swedish business life in terms of complexity, size and speed. This paper focuses on how some of the interpretative schemes of the employees were transformed during the ...
Beckerman, Carina
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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