Results 171 to 180 of about 1,893,984 (290)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

BIM-integrated life cycle assessment of decentralized cement-based waste recycling in renovation projects. [PDF]

Sci Rep
Younes A, Elbeltagi E, Ehab A, Diab A, Hamdallah M, Abazeed A.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Applying the Life Cycle Assessment to the Use of Biochar from Vine Pruning Waste as an Additive in Mortar. [PDF]

Materials (Basel)
Los Santos-Ortega J, Ferreiro-Cabello J, Fraile-García E, Somovilla-Gómez F.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Correction: Sustainable valorization of fish head wastes into nitrogen-based nutrients: a comparative life cycle assessment. [PDF]

J Biol Eng
Lee S, Ahn S, Zong JH, Oh C, Suh S, Hwang DS.   +5 more
europepmc   +1 more source

Attributional and consequential life cycle assessment of bioethanol-based PVC [PDF]

, 2012
De Meester, Steven, Dewulf, Jo, Freitas de Alvarenga, Rodrigo, Hruska, Zdenek, Martinz, Daniel, Thommeret, Richard, Van Langenhove, Herman, Villers, Joseph, Wathelet, Alain   +8 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Integrated Life Cycle Assessment Guides Sustainability in Synthesis: Antiviral Letermovir as a Case Study. [PDF]

J Am Chem Soc
Folkerts S, Hoepfner MG, Guillén-Gosálbez G, Pérez-Ramírez J, Carreira EM.   +4 more
europepmc   +1 more source

An integrated life cycle inventory for demolition processes in the context of life cycle sustainability assessment [PDF]

, 2012
Bozhilova-Kisheva, Kossara Petrova, Hu, Mingming, Olsen, Stig Irving, van Roekel, Eric   +3 more
core