Results 221 to 230 of about 1,910,644 (290)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Integrated Life Cycle Assessment Guides Sustainability in Synthesis: Antiviral Letermovir as a Case Study. [PDF]

J Am Chem Soc
Folkerts S, Hoepfner MG, Guillén-Gosálbez G, Pérez-Ramírez J, Carreira EM.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Mechanical performance and life cycle assessment of a Persian gum-waste carpet fiber soil composite for landfill bottom liners. [PDF]

Sci Rep
Mohseninia M, Ghahremani M, Fattahi SM.
europepmc   +1 more source

Life cycle assessment of woodworking equipment [PDF]

, 2010
Арефьева, О. Ю., Черемных, Н. Н.   +1 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Correction: Sustainable valorization of fish head wastes into nitrogen-based nutrients: a comparative life cycle assessment. [PDF]

J Biol Eng
Lee S, Ahn S, Zong JH, Oh C, Suh S, Hwang DS.   +5 more
europepmc   +1 more source

Life Cycle Assessment of Electricity Systems [PDF]

, 2014
Turconi, Roberto
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Utilization of electronic plastic waste as fine aggregate with and without silica fume in concrete: experimentation and life cycle assessment. [PDF]

Sci Rep
Omran S, Sisupalan S, Alyaseen A, Khan AH.   +3 more
europepmc   +1 more source