Results 41 to 50 of about 1,486,978 (306)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Rekayasa Sipil, 2022 Developing an area can be started with infrastructure development. One example of such infrastructure is an apartment with a function as a means of residence and economic development in the area around the apartment.
Muhammad Mahesa Ramadhan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
PROPERTY LIFE CYCLE COST ANALYSIS METODS
Spatial development, 2022 The minimization of the property life cycle cost as a criterion for making a decision regarding the economic feasibility of purchasing or building a certain real estate object compared to other objects with functional utility today has become a mandatory requirement of most regulatory and legal acts in Ukraine.
Oleksandr Drapikovskyi, Iryna Іvanova
openaire +1 more source
The Unseen Face of E-Business Project Development [PDF]
, 2003 The purpose of this paper is intent on identify and analyze the unseen factors of successful or failure of e-business project development. The IT managers must take into account both all costs involved in e-business development and all phases (analysis ...
A Drobik +17 more
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Structure of Cost of Equity as the Dependence on the Corporate- and Market Life Cycle [PDF]
, 2012 Purpose of the article: Companies, like all living creatures, goes through their life cycle, which includes some partial phases. Each of these phases is specific. Depending up the corporate life cycle, there are changed managerial decisions, that have an
Konečný, Zdeněk
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Current hybrid-electric powertrain architectures:Applying empirical design data to life cycle assessment and whole-life cost analysis [PDF]
, 2014 The recent introduction of hybrid-electric powertrain technology has disrupted the automotive industry, causing significant powertrain design divergence.
Burgess, Stuart C +2 more
core +2 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source