Results 51 to 60 of about 427,526 (314)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Home ownership, life cycle stage, and residential mobility [PDF]
Abstract Previous research has shown that mobility rates decline with increasing age and duration of residence. These relationships are investigated further for the case of residential mobility using residence histories obtained in interviews with 2264 Rhode Island residents.
openaire +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
O envelhecimento na atualidade: aspectos cronológicos, biológicos, psicológicos e sociais
O objetivo deste artigo é indicar aspectos que configuram o processo de envelhecimento na sociedade atual, especificamente as diferentes conceituações utilizadas para definir este processo em relação aos aspectos cronológicos, biológicos, psicológicos e ...
Rodolfo Herberto Schneider +1 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Initial stages of morphogeny and little life cycle of Indian azalea
The results of researches of morpho- and organogenesis of different sorts of Indian azaleas are given, the peculiarities of development of different sorts are marked.
A.V. Zakrasov
doaj +1 more source
Identification of corporate life-cycle stages [PDF]
Consideration of the company's activity through the stages of the life cycle is one of the modern approaches to the analysis of economic entities. There are a wide variety of methods for determining these stages, but many of them are difficult to apply in practice. In this article, an attempt to describe several applied approaches for identification of
openaire +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

