Results 131 to 140 of about 435,308 (309)
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
ResourcesUrban water management faces growing pressure from population growth, pollution, and climate variability, demanding innovative strategies to ensure long-term sustainability.
Hugo Henrique de Simone Souza +4 more
doaj +1 more source
Supply Chains in the context of Life Cycle Assessment and Sustainability [PDF]
16th International Scientific Conference - Business Logistics in Modern Management: proceedings, 2016 Production and consumption of many products are subjected to a thorough study of their evident impact on local ecosystems and global warming, with the purpose of reduction their emissions, finding product and process alternatives and/or their total suspension or penalization.
Franjković, Jelena +2 more
openaire +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Proceedings of the Conference on Production Systems and LogisticsEnvironmental sustainability is increasingly seen as a central objective of a factory in order to ensure the long-term competitiveness of industrial companies.
Philipp, Luca +7 more
doaj +1 more source
Life Cycle Impact Assessment of chemicals: relevance and feasibility of spatial differentiation for ecotoxicity and human toxicity impact assessment [PDF]
, 2011 Environmental implications of the whole supply-chain of products, both goods and services, their use, and waste management, i.e. their entire life cycle from “cradle to grave” have to be considered to achieve more sustainable production and consumption ...
HUMBERT S. +7 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source