Results 281 to 290 of about 13,140,877 (372)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Mammography at 40 saves lives: new evidence demands a global shift in breast cancer screening guidelines in Brazil. [PDF]

Rev Assoc Med Bras (1992)
Rivas FWS, Gonçalves R, Baracat EC, Soares Júnior JM.   +3 more
europepmc   +1 more source

Enhancing infection diagnostics in advanced chronic liver disease: harnessing clinical metagenomics for rapid pathogen and antimicrobial resistance detection. [PDF]

NPJ Antimicrob Resist
Mohamad M, Sergaki C, Patel VC.
europepmc   +1 more source

Beyond morphology: opportunities and pitfalls in molecular sexing of Ixodes scapularis. [PDF]

J Med Entomol
Rattanapitoon NK, Gordon CN, Sandoval KL, Rattanapitoon SK.   +3 more
europepmc   +1 more source

High-throughput single-fly LC-MS/MS for quantitative profiling of biogenic amines in Drosophila. [PDF]

PLoS One
Hori A, Nitta T, Inamori KI, Kanoh H, Kuraishi T.   +4 more
europepmc   +1 more source

Innovation below the surface: development of a canine underwater search training device for submerged scent detection. [PDF]

Front Vet Sci
Bunker P, Brewster C.
europepmc   +1 more source

Properties and Limitations of eDNA Substrates for Terrestrial Animal Monitoring. [PDF]

Mol Ecol Resour
Zhao B, Andermann T.
europepmc   +1 more source

The most conserved genome segments for life detection on Earth and other planets (Supplemental material)

, 2008
Gary Ruvkun, M. T. Zuber, Walter Gilbert, George M. Church, Michael Finney, S. S. Johnson, Christopher E. Carr, Thomas A. Isenbarger   +7 more
openalex   +1 more source

Nucleic acids detection by SERRS spectroscopy and interactions between nucleotides and Fe-Mg rich phyllosilicate mineral surfaces in the context of the origin of life

, 2012
Cécile Feuillie, DANIEL, Isabelle
openalex   +1 more source