Results 21 to 30 of about 13,140,877 (372)

CKAP4-mediated activation of FOXM1 via phosphorylation pathways regulates malignant behavior of glioblastoma cells

open access: yesTranslational Oncology, 2023
Objective: CKAP4 (Cytoskeleton Associated Protein 4) has been reported as an important regulator of carcinogenesis. A great deal of uncertainty still surrounds the possible molecular mechanism of CKAP4 involvement in GBM.
Kaiyue Xu   +11 more
doaj   +1 more source

Radiation Tolerance of Nanopore Sequencing Technology for Life Detection on Mars and Europa. [PDF]

open access: yesSci Rep, 2019
The search for life beyond Earth is a key motivator in space exploration. Informational polymers, like DNA and RNA, are key biosignatures for life as we know it. The MinION is a miniature DNA sequencer based on versatile nanopore technology that could be
Sutton MA   +8 more
europepmc   +2 more sources

Nucleic Acid Extraction and Sequencing from Low-Biomass Synthetic Mars Analog Soils for In Situ Life Detection. [PDF]

open access: yesAstrobiology, 2019
Recent studies regarding the origins of life and Mars-Earth meteorite transfer simulations suggest that biological informational polymers, such as nucleic acids (DNA and RNA), have the potential to provide unambiguous evidence of life on Mars.
Mojarro A   +7 more
europepmc   +2 more sources

Chirality in Organic and Mineral Systems: A Review of Reactivity and Alteration Processes Relevant to Prebiotic Chemistry and Life Detection Missions

open access: yesSymmetry, 2022
Chirality is a central feature in the evolution of biological systems, but the reason for biology’s strong preference for specific chiralities of amino acids, sugars, and other molecules remains a controversial and unanswered question in origins of life ...
Carina Lee   +6 more
semanticscholar   +1 more source

Advances of multiplex ligation-dependent probe amplification technology in molecular diagnostics

open access: yesBioTechniques, 2022
Multiplex ligation-dependent probe amplification (MLPA) is a multiplex copy number analysis tool which is routinely used to detect large mutations in genetic diseases.
Xiaoni Fu   +7 more
doaj   +1 more source

Fish Target Detection in Underwater Blurred Scenes Based on Improved YOLOv5

open access: yesIEEE Access, 2023
In recent years, human beings have paid more and more attention to the exploration of the underwater world. As an important part of underwater resources, fish can be detected by using the fish image data collected by underwater imaging systems, which can
Fei Wu   +5 more
doaj   +1 more source

Nucleic Acid Extraction from Synthetic Mars Analog Soils for in situ Life Detection. [PDF]

open access: yesAstrobiology, 2017
Biological informational polymers such as nucleic acids have the potential to provide unambiguous evidence of life beyond Earth. To this end, we are developing an automated in situ life-detection instrument that integrates nucleic acid extraction and ...
Mojarro A, Ruvkun G, Zuber MT, Carr CE.
europepmc   +2 more sources

Detection of Quasi-Static Trapped Human Being Using Mono-Static UWB Life-Detection Radar

open access: yesApplied Sciences, 2021
In practical situations such as hostage rescue, earthquake and other similar events, the ultra-wideband (UWB) life-detection radar echo response from the respiration motion of the trapped person is always quasi-/non-periodic in respiration frequency or ...
Kunyu Yan, Shiyou Wu, G. Fang
semanticscholar   +1 more source

Highly efficient simultaneous hydrogen evolution and organic pollutants removal using CdS decorated with CoP nanosheet under visible light

open access: yesChemical Engineering Journal Advances, 2022
Integration of hydrogen generation with organic pollutants removal under the irradiation of visible light is a promising conception in solar energy conversion and environmental protection.
Ran Chen   +5 more
doaj   +1 more source

Contamination Control for Ultra-Sensitive Life-Detection Missions

open access: yesFrontiers in Space Technologies, 2021
A key science priority for planetary exploration is to search for signs of life in our Solar System. Life-detection mission concepts aim to assess whether or not biomolecular signatures of life are present, which requires highly sensitive instrumentation.
J. Eigenbrode   +10 more
semanticscholar   +1 more source

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