Results 181 to 190 of about 2,065,566 (311)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Health-related quality-of-life evaluation in epidermolysis bullosa: a scoping review protocol. [PDF]

Syst Rev
Arias-Merino G, Benito-Lozano J, Linertová R, Alonso-Ferreira V, on behalf the BUR-EB Study Group.   +4 more
europepmc   +1 more source

Early Childhood Caries and Oral Health-Related Quality of Life: Evaluation of the Effectiveness of Single-Session Therapy Under General Anesthesia. [PDF]

Eur J Dent, 2023
Ludovichetti FS, Zuccon A, Cantatore D, Zambon G, Girotto L, Lucchi P, Stellini E, Mazzoleni S.   +7 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

An evaluation of the educational support for teachers who teach children with life limiting illness in mainstream schools

, 2012
There are increasing numbers of children living with life limiting illnesses in mainstream schools, thanks to better medical care. Life limiting illnesses in children can include (i) conditions for which curative treatment is feasible but can fail such ...
Summers, K., Robinson, S.
core  

Enhancing urban quality of life evaluation using spatial multi criteria analysis. [PDF]

Sci Rep
Zhalehdoost A, Taleai M.
europepmc   +1 more source

Real life evaluation of sodium-glucose cotransporter 2 inhibition in type 1 diabetes and the risk of diabetic ketoacidosis. [PDF]

Diab Vasc Dis Res, 2022
Stougaard EB, Kristensen PL, Kielgast U, Andersen HU, Hamid Y, Gæde PH, Søndergaard E, Dørflinger GH, Fjeldborg KK, Hansen KW, Thomsen HH, Al-Imar TMJ, Røder M, Sridhar VS, Cherney D, Rossing P, Persson F.   +16 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Multicenter real-life evaluation of the Post-CAR prognostic index for patients with large B-cell lymphoma after CAR-T failure. [PDF]

J Hematol Oncol
Farina M, Maiolo E, Ghiggi C, Angelillo P, Novo M, Quaglia FM, Schiattone L, Battista ML, Mannelli L, Tomarchio V, Lucchini E, Pagliaro L, Scapinello G, Marangon M, Pelliccia S, Sciarra R, Russo D, Zaja F.   +17 more
europepmc   +1 more source

Real-life evaluation of a COVID-19 rapid antigen detection test in hospitalized children. [PDF]

J Med Virol, 2021
Eleftheriou I, Dasoula F, Dimopoulou D, Lebessi E, Serafi E, Spyridis N, Tsolia M.   +6 more
europepmc   +1 more source