Results 141 to 150 of about 14,599,125 (298)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Correlations of life form, pollination mode and sexual system in aquatic angiosperms. [PDF]
PLoS One, 2014 Du ZY, Wang QF.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Seed dormancy-life form profile for 358 species from the Xishuangbanna seasonal tropical rainforest, Yunnan Province, China compared to world database. [PDF]
Sci Rep, 2018 Lan Q +8 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Comparative plastome analyses reveal life-form-associated selection signatures in Orchidaceae. [PDF]
BMC Plant BiolDeng X, Ni J, Lin T, Li X, Yang L, Hu H.
europepmc +1 more source