Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A introduction to the flora of Kahman Aleshtar aera (Lurestan province) [PDF]
Kahman reserve covers an area of 400 km2 situated in the northeast of Aleshtar. The reserved area presents a variety of habitats, including cliffs and rocky outcrops, piedmont plains, alluvial plains, valleys and aquatic habitats.
a Hasanvand +3 more
doaj
The comparison of dispersal rate between invasive and native species varied by plant life form and functional traits. [PDF]
Zhang B +3 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Good Life in Later Years: A Co-Produced Research Project [PDF]
The ‘A Good Life Project’ evolved as a co-production study looking at quality of life in later years. Funded by the Life Changes Trust, and in partnership with Age Scotland, researchers from the University of Stirling worked hand in hand with
Gibson, Grant +3 more
core
Invasive alien plants (IAPs) pose a significant threat to island biodiversity and severely impact ecosystems. Understanding the species–area relationship and environmental determinants of growth forms for IAP species on subtropical islands is crucial for
Yanqiu Xie +14 more
doaj +1 more source
Leaf nutrient resorption of two life-form tree species in urban gardens and their response to soil nutrient availability. [PDF]
Hu R, Liu T, Zhang Y, Zheng R, Guo J.
europepmc +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Biogeochemical niche conservatism relates to plant species diversification and life form evolution in a subtropical montane evergreen broad-leaved forest. [PDF]
Bai K +5 more
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

