Results 111 to 120 of about 1,317,127 (311)

The Plant Diversity of Cultural Habitat Islands: Aspects of the Flora of the Mystras UNESCO World Heritage Site (Greece)

open access: yesDiversity
The Mystras UNESCO World Heritage Site (MUWHS) is a medieval historical area located on a small hill facing Sparta in the Mediterranean hotspot of the Peloponnese and receives a high number of visitors annually.
Maria Panitsa   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Nucleosome landscape reflects phenotypic differences in Trypanosoma cruzi life forms. [PDF]

open access: yesPLoS Pathog, 2021
Lima ARJ   +6 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci. [PDF]

open access: yesEpigenetics Chromatin, 2022
Lima ARJ   +12 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Correction to: Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci. [PDF]

open access: yesEpigenetics Chromatin, 2022
Lima ARJ   +12 more
europepmc   +1 more source

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