Results 171 to 180 of about 1,317,127 (311)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Influence of Functional Traits of Dominant Species of Different Life Forms and Plant Communities on Ecological Stoichiometric Traits in Karst Landscapes. [PDF]

Plants (Basel)
Wang Y, Zhang L, Feng L, Fan Z, Deng Y, Feng T.   +5 more
europepmc   +1 more source

Closed Form Expression for Fatigue Life Prediction at Combined HCF/LCF Loading

, 2003
Damir Jelaska, Srečko Glodež, Srđan Podrug   +2 more
openalex   +1 more source

The e-Records Day Event "The Driving Force of Digital-Based New Life Forms: Electronic Records Management Systems" was held on 14 October.

, 2020
Burcu Yılmaz
openalex   +1 more source

Evolution of woody life form on tropical mountains in the tribe Spermacoceae (Rubiaceae) [PDF]

, 2017
Suman Neupane, Paul O. Lewis, Steven Dessein, Hunter Lee Shanks, Sushil K. Paudyal, Frederic Lens   +5 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Life forms affect beta-diversity patterns of larch forests in China. [PDF]

Plant Divers
Fang W, Cai Q, Ji C, Zhu J, Tang Z, Fang J.   +5 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

TerrANTALife 1.0 Biodiversity data checklist of known Antarctic terrestrial and freshwater life forms. [PDF]

Biodivers Data J
Pertierra LR, Varliero G, Barbosa A, Biersma EM, Convey P, Chown SL, Cowan D, De Los Rios A, Escribano-Alvarez P, Fontaneto D, Fraser C, Harris M, Hughes K, Griffiths H, le Roux P, Liu XP, Lynch H, Majewska R, Martinez PA, Molina-Montenegro M, Olalla-Tarraga MA, Peck L, Quesada A, Ronquillo C, Ropert-Coudert Y, Sancho L, Terauds A, Vianna J, Wilmotte A, Hortal J, Greve M.   +30 more
europepmc   +1 more source

Correction to ‘To concentrate or ventilate? Carbon acquisition, isotope discrimination and physiological ecology of early land plant life forms’ [PDF]

, 2013
Moritz Meyer, Ulli Seibt, Howard Griffiths   +2 more
openalex   +1 more source