Results 91 to 100 of about 2,716,139 (331)

Food availability as a major driver in the evolution of life-history strategies of sibling species. [PDF]

, 2017
Life-history theory predicts trade-offs between reproductive and survival traits such that different strategies or environmental constraints may yield comparable lifetime reproductive success among conspecifics.
Arlettaz, Arlettaz, Arlettaz, Arlettaz, Arlettaz, Arlettaz, Arlettaz, Arlettaz, Arlettaz, Bize, Bize, Bjorkvoll, Brommer, Clutton-Brock, Descamps, Eberhardt, Frick, Gaillard, Gaillard, Ghazali, Jones, Karell, Lack, Lebreton, Millar, O'Shea, Oli, Pelisson, Pfister, Promislow, Ransome, Roff, Ruedi, Saether, Schaub, Schmidt, Schorcht, Stearns, Stearns, Wilkinson   +39 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Analysing crab syndrome through the perspective of life history theory

South African Journal of Business Management
Purpose: This research aims to explain the relationships among crab syndrome, stress caused by uncertainty and organisational commitment (affective-continuance-normative) and explores unknown aspects of crab syndrome.
Burcu Üzüm, Simge Samancı, Osman Seray Özkan   +2 more
doaj   +1 more source

Reconfiguring the shipping news : Maritime's hidden histories and the politics of gender display [PDF]

, 2008
This paper discusses the book Hello Sailor! The Hidden History of Gay Life at Sea published in 2003 by Paul Baker and Jo Stanley re-interpreted as a landmark temporary, exhibition Hello Sailor!
Meecham, Pam
core   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

On answering accusations in controversies [PDF]

, 2009
Accusations are a very frequent type of speech act both in everyday life and in formal controversies, and answering accusations is a sophisticated type of linguistic practice well worth analysing from a pragmatic point of view.
Fritz, Gerd
core  

Pace of life, predators and parasites: predator-induced life-history evolution in Trinidadian guppies predicts decrease in parasite tolerance [PDF]

, 2015
A common evolutionary response to predation pressure is increased investment in reproduction, ultimately resulting in a fast life history. Theory and comparative studies suggest that short-lived organisms invest less in defence against parasites than ...
Cable, J., Stephenson, J. F., van Oosterhout, C.   +2 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The attractiveness of the project of practical methodology and virtue epistemology for the economic history research [PDF]

, 2017
Ewa Domańska, a distinguished historian of historiography and the methodologist of history, has provided an insightful commentary on the state of humanities and social sciences.
Bębnowski, Damian
core   +1 more source