Results 111 to 120 of about 2,716,139 (331)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
2. Toynbee and the Cyclical Pattern of History
, 1958 There has been recently a return on the part of some writers to the Greek theory that the course of history follows a cyclical pattern. An important motivation for this return is the conviction that neither the theory of progress nor the classical ...
Bloom, Robert L. +6 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Symmetry and The Creative Cognition [PDF]
, 2006 An unconquered conceptual divide related to cognitive perception exists between the physical and biological sciences. The life processes of self assembly and replication are unaccounted for in quantum theory or in the ordinary laws of physics.
Kirsh, Dr. Marvin/E.
core
Stochastic and deterministic models for age-structured populations with genetically variable traits
, 2009 Understanding how stochastic and non-linear deterministic processes interact is a major challenge in population dynamics theory. After a short review, we introduce a stochastic individual-centered particle model to describe the evolution in continuous ...
C. Besse +5 more
core +3 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Are Expectations the Missing Link between Life History Strategies and Psychopathology?
Frontiers in Psychology, 2018 Despite advances in knowledge and thinking about using life history theory to explain psychopathology there is still a missing link. That is, we all have a life history strategy, but not all of us develop mental health problems.
Phillip S. Kavanagh +3 more
doaj +1 more source
Borderline Personality Disorder in a "Life History Theory" Perspective: Evidence for a Fast "Pace-of-Life-Syndrome". [PDF]
Front Psychol, 2021 Otto B, Kokkelink L, Brüne M.
europepmc +1 more source