Results 171 to 180 of about 2,716,139 (331)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Childhood risks and problematic smartphone use: Dual processes of life history strategy and psychological distress

Cyberpsychology: Journal of Psychosocial Research on Cyberpspace
Problematic smartphone use (PSU) and its negative consequences among adolescents are so commonly observed that they have become a matter of public concern.
Meng Xuan Zhang, Lisbeth Ku, Anise M. S. Wu   +2 more
doaj  

demogR: A Package for the Construction and Analysis of Age-structured Demographic Models in R

Journal of Statistical Software, 2007
The analysis of matrix population models has become a fundamental tool in ecology, conservation biology, and life history theory. In this paper, I present demogR, a package for analyzing age-structured population models in R.
James Holland Jones
doaj  

Putting life history theory to the test - the estimation of reproductive values from field data

, 2022
Borger MJ, Komdeur J, Richardson DS, Weissing FJ.   +3 more
europepmc   +1 more source

Nest defence behavioural reaction norms: testing life-history and parental investment theory predictions

, 2019
Bert Thys, Yorick Lambreghts, Rianne Pinxten, Marcel Eens   +3 more
openalex   +1 more source

Adaptation and plasticity in life-history theory: How to derive predictions.

, 2020
Matthias Galipaud, Hanna Kokko
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

The evolution of life-history theory: a bibliometric analysis of an interdisciplinary research area. [PDF]

Proc Biol Sci, 2019
Nettle D, Frankenhuis WE.
europepmc   +1 more source

Exobiology experiment concepts for space station [PDF]

The exobiology discipline uses ground based and space flight resources to conduct a multidiscipline research effort dedicated to understanding fundamental questions about the origin, evolution, and distribution of life and life related molecules ...
Devincenzi, D. L., Griffiths, L. D.
core   +1 more source