Results 71 to 80 of about 2,758,289 (295)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Position of Body Mass in a Network of Human Life History Indicators
Body mass is widely recognized as a morphological trait which is important for fitness optimization both in humans and other animals. Here, we propose that body mass is a part of fast life history trajectory – the fitness optimization pattern which ...
Janko Međedović
doaj +2 more sources
Modern humans have more fragile skeletons than other hominins, which may result from physical inactivity. Here, we test whether reproductive effort also compromises bone strength, by measuring using computed tomography thoracic vertebral bone mineral ...
Jonathan Stieglitz +7 more
doaj +1 more source
Material security, life history, and moralistic religions: A cross-cultural examination. [PDF]
Researchers have recently proposed that "moralistic" religions-those with moral doctrines, moralistic supernatural punishment, and lower emphasis on ritual-emerged as an effect of greater wealth and material security.
Benjamin Grant Purzycki +9 more
doaj +1 more source
On answering accusations in controversies [PDF]
Accusations are a very frequent type of speech act both in everyday life and in formal controversies, and answering accusations is a sophisticated type of linguistic practice well worth analysing from a pragmatic point of view.
Fritz, Gerd
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
“The weight we carry in our backpack is not the weight of our books, it’s the weight of our community!”: Latinas negotiating identity and multiple roles [PDF]
In the United States, out of 100 Latina/o elementary students, only 0.3 will complete a doctorate degree. Latinas/os/x as a fast-growing minority population in the United States continue to be underrepresented in higher education. The underrepresentation
Camargo Gonzalez, Lorena
core
Endogenous ROS Levels in C. Elegans Under Exogenous Stress Support Revision of Oxidative Stress Theory of Life-History Tradeoffs [PDF]
Background: The oxidative stress theory of life-history tradeoffs states that oxidative stress caused by damaging free radicals directly underpins tradeoffs between reproduction and longevity by altering the allocation of energetic resources between ...
Denver, Dee R. +3 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Uneven and combined development: modernity, modernism, revolution [PDF]
Trotsky’s theory of Uneven and Combined Development was born out of his experience of the Russian Revolution. To mark the centenary of the revolution, we are publishing a series of five pieces by Neil Davidson that explore the theory’s wider contribution
Davidson, Neil
core

