Results 81 to 90 of about 2,716,139 (331)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The Position of Body Mass in a Network of Human Life History Indicators
Body mass is widely recognized as a morphological trait which is important for fitness optimization both in humans and other animals. Here, we propose that body mass is a part of fast life history trajectory – the fitness optimization pattern which ...
Janko Međedović
doaj +2 more sources
Between Duty and Romance: The Attraction of Sounding “Black” in Paris [PDF]
The histories of Black Americans who significantly influenced French life and culture in Paris are hardly marked or visible across the most frequented tourist destinations or within state-sponsored museums dedicated to national history.
Wilson, Anndretta Lyle
core
The Life and Legacy of James I, King of England [PDF]
As the first member of the Stuart line to hold the Kingdoms of England, Ireland, and Scotland under his suzerainty, the life and reign of King James I was always going to mark a serious turning point in the histories of the lands under his control.
Arbaugh, Nicholas S.
core +1 more source
Friend and foe: factors influencing the movement of the bacterium Helicobacter pylori along the parasitism-mutualism continuum. [PDF]
Understanding the transition of bacterial species from commensal to pathogen, or vice versa, is a key application of evolutionary theory to preventative medicine.
Koskella, Britt, Lin, Derek
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Some Evidence for an Association Between Early Life Adversity and Decision Urgency
The relationship between early life adversity and adult outcomes is traditionally investigated relative to risk and protective factors (e.g., resilience, cognitive appraisal), and poor self-control or decision-making.
Johanne P. Knowles +2 more
doaj +1 more source
Uneven and combined development: modernity, modernism, revolution [PDF]
Trotsky’s theory of Uneven and Combined Development was born out of his experience of the Russian Revolution. To mark the centenary of the revolution, we are publishing a series of five pieces by Neil Davidson that explore the theory’s wider contribution
Davidson, Neil
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

