Results 171 to 180 of about 679,610 (316)
Research on the drilling pipe health monitoring and intelligent life prediction management platform. [PDF]
Sci RepGao X, Wu X, Li Q, Wang L, Zhu Z, Qu F.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
One-year reserve risk including a tail factor: closed formula and bootstrap approaches [PDF]
In this paper, we detail the main simulation methods used in practice to measure one-year reserve risk, and describe the bootstrap method providing an empirical distribution of the Claims Development Result (CDR) whose variance is identical to the closed-
Yoboua Angoua +3 more
core
Trans-D3: A Novel Hybrid Transformer-Based Actor-Critic Approach for Remaining Useful Life Prediction. [PDF]
Sensors (Basel)Paredes J +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
, 2013 The influence of environmental medias on crack propagation of a structural steel at high and very-high-cycle fatigue (VHCF) regimes is investigated based on the fatigue tests performed in air, water and 3.5% NaCl aqueous solution.
Zhou CE(周承恩) +3 more
core
Uncertainty-Aware Remaining Useful Life Prediction via Synergizing TCN-Transformer Networks and Fractional Brownian Motion. [PDF]
Entropy (Basel)Geng Y, Yu T, Liu Y, Zhao J.
europepmc +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Remaining useful life prediction method based on gated dilation causal convolution. [PDF]
Sci RepHe J, Sun W, Zhang C.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source