Results 251 to 260 of about 9,230,198 (341)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Emotional disturbances and psychological resilience among earthquake survivors in temporary shelters: assessing the role of life satisfaction. [PDF]

BMC Psychol
Gökkaya E, Topal MH, Demirbilek Ö, Baydemir MB.   +3 more
europepmc   +1 more source

From Pores to Pavement: Advanced Modeling of Aluminosilicates for Scalable Carbon Capture in Concrete

Advanced Science, EarlyView.
This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair, Jéssica de O. N. Ribeiro, Murilo Daniel de Mello Innocentini, Kevin Paine, Juliana Calabria‐Holley   +4 more
wiley   +1 more source

Problematic Internet use and life satisfaction: a moderated mediation model with social appearance anxiety as mediator and impulsivity as moderator. [PDF]

Front Psychol
Aras E.
europepmc   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Influencing factors and sex differences of life satisfaction in patients with chronic kidney disease: a national cross-sectional study in China. [PDF]

BMJ Open
Shen K, Ji X, Zhang Y, Cheng Y, Xian X.
europepmc   +1 more source

Resilience, Life Satisfaction, and Well-Being in Portuguese Adolescents: A Cross-Sectional Study. [PDF]

Behav Sci (Basel)
Loureiro L, Loureiro C, Santos J.
europepmc   +1 more source

Social Participation and Life Satisfaction of Employees in the Academe using Online Survey and Key Informant Interview. [PDF]

Acta Med Philipp
Fiestada JF, Ladia MAJ.
europepmc   +1 more source

The mediating role of motivation in the relationship between emotional intelligence and life satisfaction: an empirical study on teachers. [PDF]

Front Psychol
Han B.
europepmc   +1 more source