Results 221 to 230 of about 8,033,101 (355)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

DIY liquid handling robots for integrated STEM education and life science research. [PDF]

open access: yesPLoS One, 2022
Li E   +7 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Brilliant life in science

open access: yesІнтродукція Рослин, 2006
T.M. Cherevchenko   +8 more
doaj   +1 more source

A group-forming course content-focused icebreaker for life science classrooms. [PDF]

open access: yesJ Microbiol Biol Educ
Kleinschmit AJ   +2 more
europepmc   +1 more source

FAIR environmental and health registry (FAIREHR)- supporting the science to policy interface and life science research, development and innovation. [PDF]

open access: yesFront Toxicol, 2023
Zare Jeddi M   +36 more
europepmc   +1 more source

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