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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Using text-mining to measure the scientific impact and legacy of ELIXIR, a distributed research infrastructure for life science data. [PDF]
F1000ResDe Leo F +7 more
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The Science of Meaning in Life
Annual Review of Psychology, 2021Meaning in life has long been a mystery of human existence. In this review, we seek to demystify this construct. Focusing on the subjective experience of meaning in life, we review how it has been measured and briefly describe its correlates. Then we review evidence that meaning in life, for all its mystery, is a rather commonplace experience. We then
Laura A, King, Joshua A, Hicks
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Computer Physics Communications, 2002
The advent of powerful computers and algorithms combined with new, powerful ways of thinking about problems in statistical physics has created an unprecedented opportunity for making significant breakthroughs in a variety of interdisciplinary problems, most notably in the life sciences.
J. R. BANAVAR, MARITAN, AMOS
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The advent of powerful computers and algorithms combined with new, powerful ways of thinking about problems in statistical physics has created an unprecedented opportunity for making significant breakthroughs in a variety of interdisciplinary problems, most notably in the life sciences.
J. R. BANAVAR, MARITAN, AMOS
openaire +1 more source
Science, 2000
H. Gobind Khorana was born in 1922 in Raipur, Punjab, India (now Pakistan). He trained as an organic chemist, and was awarded the Nobel Prize for Physiology or Medicine in 1968, together with Robert W. Holley and Marshall W. Nirenberg, "for their interpretation of the genetic code and its function in protein synthesis." In this essay, Khorana recounts ...
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H. Gobind Khorana was born in 1922 in Raipur, Punjab, India (now Pakistan). He trained as an organic chemist, and was awarded the Nobel Prize for Physiology or Medicine in 1968, together with Robert W. Holley and Marshall W. Nirenberg, "for their interpretation of the genetic code and its function in protein synthesis." In this essay, Khorana recounts ...
openaire +2 more sources
New Generation Computing, 2007
Grid and the Grid computing paradigm have the potential to become “the” model for the standard cyberinfrastructure for life science research. The vision of providing seamless and transparent access to high-performance computing resources and management of large scale post-genomic data sets, coupled with solutions overcoming inter-organizational ...
Akihiko Konagaya +2 more
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Grid and the Grid computing paradigm have the potential to become “the” model for the standard cyberinfrastructure for life science research. The vision of providing seamless and transparent access to high-performance computing resources and management of large scale post-genomic data sets, coupled with solutions overcoming inter-organizational ...
Akihiko Konagaya +2 more
openaire +1 more source