Results 41 to 50 of about 8,033,101 (355)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Integrated Science through Computer-aided Experiments

Informatics in Education, 2004
The paper outlines curriculum development activities that have been done in science education in the Slovak Republic as a result of an international collaboration within the frame of the Leonardo da Vinci II pilot project Computerised Laboratory in ...
Stanislav HOLEC, Martin HRUSKA, Jana RAGANOVÁ   +2 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Memories for Life: A Review of the Science and Technology

, 2006
This paper discusses scientific, social and technological aspects of memory. Recent developments in our understanding of memory processes and mechanisms, and their digital implementation, have placed the encoding, storage, management and retrieval of ...
Beagrie, Neil, Hall, Wendy, Hitch, Graham J., Morris, Richard, O'Hara, Kieron, Shadbolt, Nigel   +5 more
core   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

A user-guided Bayesian framework for ensemble feature selection in life science applications (UBayFS) [PDF]

, 2022
Anna Jenul, Stefan Schrunner, Jürgen Pilz, Oliver Tomić   +3 more
openalex   +1 more source

Differences in Persistence Patterns Between Life and Physical Science Majors: The Role of Grades, Peers, and Preparation [PDF]

, 2010
Using longitudinal administrative data from a large elite research university, this paper separately analyzes the determinants of persistence for life and physical science majors.
Ost, Ben
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Gender, Equity, and Science Writing: Examining Differences in Undergraduate Life Science Majors’ Attitudes toward Writing Lab Reports

Education Sciences
It is often causally generalized that females naturally excel more at writing than males. Contrastingly, modern conventional wisdom similarly purports that males often innately excel more at science.
Kristy M. Palmer, Mark A. Perkins, Timothy F. Slater   +2 more
doaj   +1 more source

Samarbeidsklimaendringer. Om humanistiske og filosofiske livsbetingelser i en posthumanistisk tid

Norsk Filosofisk Tidsskrift, 2018
«Posthumanisme» er et begrep med økende utbredelse og (minst) to betydninger: For det første lever vi i en tid der menneskelivet – sett med naturvitenskapelig blikk – får stadig mer uklare grenseflater mot andre livsformer.
Jan Grue
doaj   +1 more source