Results 71 to 80 of about 8,033,101 (355)
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
Data-Driven Paradigm: A Study on the Evolution of Research Paradigms in Life Science
Yixue yu zhexueData-driven paradigms have propelled a profound evolution in research methodologies within the life sciences. With advances in information technology and the emergence of high-throughput data, the field has exhibited a synergistic evolution from the ...
Gang QIN, Jianhui LI
doaj +1 more source
Causal Constraints in the Life and Social Sciences [PDF]
, 2023 Lauren N. Ross
openalex +1 more source
Exobiology and life science [PDF]
The following types of experiments for a proposed Space Station Microgravity Particle Research Facility are described: (1) biogenic elements in the interstellar medium; (2) organic material in the solar nebula; (3) volatiles in comets and icy ...
Mckay, C. P.
core +1 more source
The sciences in America, circa 1880 [PDF]
, 1980 For many years American science in the late 19th century was regarded as an intellectual backwater. This view derived from the assumption that the health of American science at the time was equivalent to the condition of pure science, especially pure ...
Carroll, P. Thomas +2 more
core +2 more sources
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Life science payloads planning study [PDF]
Preferred approaches and procedures were defined for integrating the space shuttle life sciences payload from experiment solicitation through final data dissemination at mission completion. The payloads operations plan was refined and expended to include
Nelson, W. G., Wells, G. W.
core +1 more source
Frontier of life science [PDF]
Journal of Molecular Cell Biology, 2013 Cheng, Z., Ito, S., Nishio, N., et al. (2011). Establishment of induced pluripotent stem cells from aged mice using bone marrow-derived myeloid cells. J. Mol. Cell Biol. 3, 91–98.
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Where there is life there is mind: In support of a strong life-mind continuity thesis [PDF]
, 2017 This paper considers questions about continuity and discontinuity between life and mind. It begins by examining such questions from the perspective of the free energy principle (FEP).
Froese, Tom, Kirchhoff, Michael David
core +2 more sources