Results 71 to 80 of about 249,708 (285)

Public entities driven robotic innovation in urban areas [PDF]

, 2017
Cities present new challenges and needs to satisfy and improve lifestyle for their citizens under the concept “Smart City”. In order to achieve this goal in a global manner, new technologies are required as the robotic one.
Bolea Monte, Yolanda, Casanovas Garcia, Josep, Grau Saldes, Antoni, Puig-Pey Clavería, Ana María   +3 more
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

German Cancer Consortium (DKTK) – A national consortium for translational cancer research

Molecular Oncology, 2019
The German Cancer Consortium (‘Deutsches Konsortium für Translationale Krebsforschung’, DKTK) is a long‐term cancer consortium, bringing together the German Cancer Research Center (DKFZ), Germany's largest life science research center, and the leading ...
Stefan Joos, Dirk M. Nettelbeck, Anette Reil‐Held, Katja Engelmann, Alexandra Moosmann, Angelika Eggert, Wolfgang Hiddemann, Mechthild Krause, Christoph Peters, Martin Schuler, Klaus Schulze‐Osthoff, Hubert Serve, Wolfgang Wick, Josef Puchta, Michael Baumann   +14 more
doaj   +1 more source

Implementing Open Access Policy: First case studies [PDF]

, 2011
When implementing open access, policy pioneers and flagship institutions alike have faced considerable challenges in meeting their own aims and achieving a recognized success.
ARMBRUSTER, Chris, Chris Armbruster (E-mail: armbruster@mpdl.mpg.de)   +1 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

EGI: anOpen e-Infrastructure Ecosystem for the Digital European Research Area [PDF]

, 2012
Bringing the digital European Research Area (ERA) online means modernising Europe’s research infrastructure by promoting open science through the availability, accessibility and reuse of scientific data and results, the use of web- based tools that ...
Andreozzi, Sergio, Holsinger, Sy, Marinovic, Damir, Newhouse, Steven   +3 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Drivers of Bacterial α- and β-Diversity Patterns and Functioning in Subsurface Hadal Sediments

Frontiers in Microbiology, 2019
Oceanic trenches at hadal (>6,000 m) depths are hot spots of organic matter deposition and mineralization and can host abundant and active bacterial assemblages.
Eugenio Rastelli, Cinzia Corinaldesi, Antonio Dell’Anno, Michael Tangherlini, Marco Lo Martire, Manabu Nishizawa, Hidetaka Nomaki, Takuro Nunoura, Roberto Danovaro, Roberto Danovaro   +9 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Toxicological Risk Analysis in Data-Poor Countries: A Narrative Approach to Feed an “Awareness Raising—Community Empowerment” Vortex

Medicina, 2020
Background and objectives: With globalization of culture and products, choices and behaviors associated with the unawareness of toxicological risk factors result in human and environmental toxic exposures along with health disparities.
Chiara Frazzoli
doaj   +1 more source