Results 251 to 260 of about 15,808,373 (394)

Image 3_How math shapes the world of life science animation.tif

open access: green
Rafael Oliveira (6619367)   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

A comprehensive evaluation of life sciences data resources reveals significant accessibility barriers. [PDF]

open access: yesSci Rep
L'Yi S   +7 more
europepmc   +1 more source

Parallel Algorithms for Multirelational Data Mining: Application to Life Science Problems

open access: gold, 2016
Rui Camacho   +5 more
openalex   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Organ medicine: New concept of life sciences. [PDF]

open access: yesChin Med J (Engl)
Chen Z   +7 more
europepmc   +1 more source

The Impact of Life Sciences Developments on the UK Urban Environment

open access: hybrid, 2016
Peter Jones   +3 more
openalex   +1 more source

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