Results 61 to 70 of about 2,264,386 (292)
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Background: Blockchain and distributed ledger technology is a disruptive force in healthcare. Methods: This article provides a globally relevant, interdisciplinary perspective intended to aid disparate group of actors, participants, and users that ...
Ron Ribitzky+8 more
doaj +1 more source
The Nature of Science and Other Lectures By Edwin Hubble. Pp. viii + 83 + 2 plates. (San Marino, Calif.: The Huntington Library, 1954.) 2 dollars.
openaire +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Zootechnical sciences represent a well defined concept since the notion of “Zootechnics” has been in use (in the second part of the 19th c.) and they continued to develop throughout the 20th century and they have acquired new insights in the early 21st c.
Alexandru T. Bogdan+2 more
doaj
Microfluidics and the Life Sciences
The field of microfluidics, often also referred to as “Lab-on-a-Chip” has made significant progress in the last 15 years and is an essential tool in the development of new products and protocols in the life sciences. This article provides a broad overview on the developments on the academic as well as the commercial side.
Claudia Gärtner, Holger Becker
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This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Scientometric Analysis: An Emerging Tool in Veterinary and Animal Scientific Research
The present study is an evaluation of published papers in the field of scientometrics–bibliometrics in veterinary or animal studies. The objective was the quantitative evaluation of the scientific content and the bibliometric details of papers that had ...
Georgia A. Vaitsi+6 more
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source