Results 31 to 40 of about 39,862 (302)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A City for All: The Future of Human Settlements in Latin America and the Caribbean
The report presents a regional synopsis on the state of urban management in Latin America and the Caribbean for participants of the Second United Nations Conference on Human Settlements (Habitat II) in Istanbul (1996).
Inter-American Development Bank
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Spatial organization of the settlement network of the municipality of Čačak and tendencies of its development [PDF]
The balanced and sustainable development of the functional area of Čačak is a precondition for greater integration of geospace. Based on the fact that settlements are the most striking elements of the cultural landscape and they are the holders ...
Nikolić Teodora
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
This paper synthesizes the historical trajectory of the altiplano societies of the northern Titicaca Basin, Department of Puno, Peru. These societies began as permanent village settlements organized at the community level and then developed into state ...
Henry Tantaleán, María Ysela Leyva
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Amish Settlements across America: 2013 [PDF]
This short research report is based upon previous editions of “Amish Settlements across North America,” which was published periodically in Family Life.
Donnermeyer, Joseph, Luthy, David
core +2 more sources
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

