Results 131 to 140 of about 8,857,148 (250)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The importance of Life and Soft Skills: how they are promoted among young people.

open access: yes
openCi troviamo in un epoca composta da continui cambiamenti, in cui è sempre più richiesta la presenza di persone capaci, preparate ad agire in qualsiasi situazione in modo autonomo e consapevole.
FANTIN, SARA
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Skills for Life Series: Empathy & Compassion

open access: yes
Empathy and compassion are vital skills for emotional and social development, motivating prosocial behaviors and effective conflict resolution. Empathy involves understanding others\u27 emotions, while compassion drives actions to alleviate their ...
Inter-American Development Bank
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Promoting life skills in adolescents through sport: assessment tools, training, and the role of coaches

open access: yes
openTitolo: "Promuovere le life skills negli adolescenti attraverso lo sport: strumenti di valutazione, formazione e ruolo degli allenatori" Questa tesi esplora il potenziale dello sport come contesto privilegiato per lo sviluppo delle life skills ...
ZERBATO, ANNA
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Editorial: Life skills in school health promotion: challenges and solutions. [PDF]

open access: yesFront Public Health
Carvalho GS   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy