Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Analysis of covariance and sample size calculation for comparing means in randomized controlled trials [PDF]
Yousef Alimohamadi, Mojtaba Sepandi
doaj +1 more source
Structural Equations Modeling of Life Skills and Attachment Styles with Marital Conflicts: the Mediating Role of Sexual Satisfaction and Couples' Love Stories [PDF]
Elaheh Soleimani +3 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
3. Edmund Burke and Conservatism
Edmund Buxke (1729-1797) has often been compared to John Wesley, and there are several bases for such a comparison. Both infused a new life and meaning into the coin temporary formal structure of politics and religion, respectively.
Bloom, Robert L. +6 more
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Non-Insulin Therapeutic Option in Management of Diabetes: Life Style Modification; Diet and Exercise
Udaya M. Kabadi
openalex +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Life-style orientation and contents of websites in personas industry [PDF]
Electronic commerce challenges personas companies to design electronic system to increase interaction which leads to retain customers and increase sales.
Chien-Ta (Bruce) HO +2 more
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
HOUSING MODEL AND URBAN LIFE STYLE [PDF]
Joint Research on Environmental Science and Technology for the ...
Vu, Hao Quang
core

