Results 111 to 120 of about 8,714,418 (337)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Analysis of covariance and sample size calculation for comparing means in randomized controlled trials [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2023
Yousef Alimohamadi, Mojtaba Sepandi
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

3. Edmund Burke and Conservatism

open access: yes, 1958
Edmund Buxke (1729-1797) has often been compared to John Wesley, and there are several bases for such a comparison. Both infused a new life and meaning into the coin temporary formal structure of politics and religion, respectively.
Bloom, Robert L.   +6 more
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Life-style orientation and contents of websites in personas industry [PDF]

open access: yes
Electronic commerce challenges personas companies to design electronic system to increase interaction which leads to retain customers and increase sales.
Chien-Ta (Bruce) HO   +2 more
core  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

HOUSING MODEL AND URBAN LIFE STYLE [PDF]

open access: yes, 2006
Joint Research on Environmental Science and Technology for the ...
Vu, Hao Quang
core  

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