Results 111 to 120 of about 2,278,753 (349)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Determining the combined effects of three weeks of consumption of HMB supplement and one session of extreme eccentric resistance exercise on the expression rates of myoG and CD56 genes in satellite cells

open access: yesRevista Brasileira de Nutrição Esportiva, 2019
The purpose of the present study was to determine the combined effects of consumption of HMB-FA supplement and one session of extreme Eccentric resistance training on the rate of activation of the satellite cells of mature male rats.
Elias Kowsari   +4 more
doaj  

A Program of Life-Style Modification Improved the Body Weight and Micronutrient Status in Obese Patients after Bariatric Surgery. [PDF]

open access: yesNutrients, 2023
Crespo-Yanguas M   +5 more
europepmc   +1 more source

Children\u27s Effortful Control in a Montessori Classroom: Effects of Parenting and Purposeful Work [PDF]

open access: yes, 2012
Research in effortful control is necessary to understand and support children\u27s behaviors in Social and classroom settings (Rimm-Kaufman, Curby, Grimm, Brock, & Nathanson, 2009).
Blahut, Judith Sarah
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Prevalence and antibiotic resistance of Staphylococcus aureus associated with a college-aged cohort: life-style factors that contribute to nasal carriage. [PDF]

open access: yesFront Cell Infect Microbiol, 2023
Congdon ST   +11 more
europepmc   +1 more source

Changing my life one step at a time – using the Twelve Step program as design inspiration for long term lifestyle change [PDF]

open access: yes, 2012
To explore how people manage and maintain life style change, we conducted interviews with eight members of different Twelve Step Fellowships with 2-23 years of recovery about how they maintain and develop their recovery in everyday life.
Nylander, Stina
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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