Results 111 to 120 of about 9,584,915 (340)

Kiran Bedi’s Innovative Initiatives and Leadership Practices in Puducherry, India [PDF]

open access: yes, 2019
The purpose of this research paper is to outline innovative initiatives and leadership practices by Kiran Bedi, the Lt. Governor of Puducherry, India to achieve good governance. It unveils leadership challenges and offers leadership lessons.
Rao, M. S.
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

HOUSING MODEL AND URBAN LIFE STYLE [PDF]

open access: yes, 2006
Joint Research on Environmental Science and Technology for the ...
Vu, Hao Quang
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Kualitas Produk Sebagai Variabel Intervening Antara Pengaruh Life Style Terhadap Minat Beli Mobil Agya Di Pasaman Barat [PDF]

open access: yes, 2016
This study aimed to see how the variables Lifestyle affect intantion and see also whether the Quality of Product role as an intervening variable. From the results of this study, the variables Life Style (X) significantly affects Intantion (Y), where the ...
Mantauv, C. S. (Citra)
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Investigation of the Combined Effects of workplace physical agents and shift work on Physiological parameters and blood factors in nurses

open access: yesInternational Journal of Occupational Hygiene, 2022
Since nurses spend most of their working time indoors, the quality of the hospital environment has a great impact on their performance and comfort. The aim of this study was to investigate the combined effects of physical factors in the workplace and ...
keivan saedpanah   +4 more
doaj  

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