Results 71 to 80 of about 2,161,779 (334)

The impact of the national vaccination program on COVID-19 Infection Trends in Iran: An interrupted time series analysis [PDF]

open access: yesفصلنامه ابن سینا
Background and aims: Various methods have been employed globally to prevent the spread of COVID-19. However, the effectiveness of vaccination in reducing COVID-19 infections requires further investigation.
Kolsoom Alimohamadi   +2 more
doaj  

The Role of Histamine H1 and H4 Receptors in Atopic Dermatitis: From Basic Research to Clinical Study

open access: yesAllergology International, 2014
Histamine plays important roles in inflammation and nervous irritability in allergic disorders, including atopic dermatitis (AD). It has been shown to regulate the expression of pruritic factors, such as nerve growth factor and semaphorin 3A, in skin ...
Yusuke Ohsawa, Noriyasu Hirasawa
doaj   +1 more source

In search of an evolutionary coding style [PDF]

open access: yes, 2000
In the near future, all the human genes will be identified. But understanding the functions coded in the genes is a much harder problem. For example, by using block entropy, one has that the DNA code is closer to a random code then written text, which in
Lundh, Torbjörn
core   +2 more sources

Bringing Impressionism to Life with Neural Style Transfer in Come Swim

open access: yes, 2017
Neural Style Transfer is a striking, recently-developed technique that uses neural networks to artistically redraw an image in the style of a source style image. This paper explores the use of this technique in a production setting, applying Neural Style
Joshi, Bhautik   +2 more
core   +1 more source

Reminiscence and ageing [PDF]

open access: yes, 1998
This paper questions assumptions about reminiscence and looks at definitions of it. Functions of different types of reminiscence are examined and distinctions are drawn between these and autobiographical memories. Methodologies of eliciting reminiscences
Cohen, Gillian, Taylor, Stephanie
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Creating a Northern Agriculture. V. An Agroeuthenics Approach to Development in Alaska. [PDF]

open access: yes, 1976
Grateful acknowledgment is extended to Dr. A. L. Brundage, Chairman of the Publications Committee, for drawing the flow charts in this publication.The growing national concern for a better environment and more rewarding life-style is being reflected ...
Burton, Wayne E.
core  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Inhibition of thymic stromal lymphopoietin production by FK3453

open access: yesJournal of Pharmacological Sciences, 2022
To prevent the onset and aggravation of allergic diseases, it is necessary to modulate excessive Th2-type immune responses. It is well accepted that thymic stromal lymphopoietin (TSLP) plays important roles in the change of Th1/Th2 balance to Th2 ...
Ryosuke Segawa   +3 more
doaj  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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