Results 71 to 80 of about 2,278,753 (349)
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
The impact of the national vaccination program on COVID-19 Infection Trends in Iran: An interrupted time series analysis [PDF]
فصلنامه ابن سیناBackground and aims: Various methods have been employed globally to prevent the spread of COVID-19. However, the effectiveness of vaccination in reducing COVID-19 infections requires further investigation.
Kolsoom Alimohamadi +2 more
doaj
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
HUBUNGAN ANTARA GAYA HIDUP HEDONIS DENGAN PERILAKU DISSAVING (BERHUTANG) PADA MAHASISWA DI MALANG [PDF]
, 2009 Life style is behavior of someone posed at in activities (activity), interest (enthusiasm) and opinion (opinion) type life style which many enthused circle [by] the student in Malang one of them is life style type hedonis, because this life style type ...
Tri Nugrahaini, Yulia
core
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
Does Health Class Affect Students\u27 Decision Making? [PDF]
, 2012 The effectiveness of high school health education curriculum which is evaluated through anonymous student response in a behavior and life style survey that is given before students take health education and again after they have taken health education to
Aiello, Taylor
core +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
آموزش بهداشت و ارتقاء سلامت ایران, 2019 Background and Objective: A basic intervention to reduce prevalence of the disease is educating healthy lifestyle particularly for those who are at risk.
Mohsen Saffari +6 more
doaj