Results 71 to 80 of about 7,010,849 (257)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reasonable consumption against consumer life style [PDF]

open access: yes, 2012
This thesis deals with the analysis of two opposing present-day life styles. The first one is so called reasonable consumption or voluntary simplicity, which is nowadays often realized in an environmental life style with the focus on its actual forms in ...
Reitmaierová, Lucie
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Comparison Between Impact of a Health Education Program Using In-situ Training and Text-Messaging on Lifestyle and Blood Pressure in Military Personnel at Risk of Hypertension

open access: yesآموزش بهداشت و ارتقاء سلامت ایران, 2019
Background and Objective: A basic intervention to reduce prevalence of the disease is educating healthy lifestyle particularly for those who are at risk.
Mohsen Saffari   +6 more
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Trends, prevalence, incidence, and disability-adjusted life years of anorexia nervosa and bulimia nervosa in Iran: Global Burden of Disease Study

open access: yesEating and Weight Disorders
Objectives Given the significant prevalence of mental health disorders in Iran, this research seeks to examine various epidemiological aspects related to eating disorders (ED).
Sohrab Amiri, Seyed Morteza Hosseini
doaj   +1 more source

The Role of Histamine H1 and H4 Receptors in Atopic Dermatitis: From Basic Research to Clinical Study

open access: yesAllergology International, 2014
Histamine plays important roles in inflammation and nervous irritability in allergic disorders, including atopic dermatitis (AD). It has been shown to regulate the expression of pruritic factors, such as nerve growth factor and semaphorin 3A, in skin ...
Yusuke Ohsawa, Noriyasu Hirasawa
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Analysis of covariance and sample size calculation for comparing means in randomized controlled trials [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2023
Yousef Alimohamadi, Mojtaba Sepandi
doaj   +1 more source

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