Results 71 to 80 of about 7,501,597 (301)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Comparison Between Impact of a Health Education Program Using In-situ Training and Text-Messaging on Lifestyle and Blood Pressure in Military Personnel at Risk of Hypertension

آموزش بهداشت و ارتقاء سلامت ایران, 2019
Background and Objective: A basic intervention to reduce prevalence of the disease is educating healthy lifestyle particularly for those who are at risk.
Mohsen Saffari, Hormoz Sanaeinasab, Hojat Rashidi-Jahan, Mohammad-hassan Hajijafar-Namazi, Mojtaba Sepandi, Mohammad Samadi, Esfandiar Azad-Marzabadi   +6 more
doaj  

Parenting Style

, 2014
Parenting style is conceptualized as a constellation of attitudes or a pattern of parental authority towards the child which are conveyed to the child, creating the emotional context for the expression of parent behavior.
Tsang, SKM, Cynthia Leung, Leung, C, Sandra Tsang Kit Man   +3 more
core   +1 more source

style-rec-data.tar.gz

, 2023
Email dataset using emails from reallygoodemails.com converted to graph and hypergraph. Eight node classes are extracted: button-style, bg-style-font, text-style, background-style, entire-fragment, word, button-text, and image.
Ryan Rossi (13900294), Nedim Lipka (13900300), Nesreen K. Ahmed (14440533), Gromit Chan (13900296), Jane Hoffswell (13900297), Ryan Aponte (13900290), Shunan Guo (13900331), Chang Xiao (14440530), Eunyee Koh (13900302)   +8 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Trends, prevalence, incidence, and disability-adjusted life years of anorexia nervosa and bulimia nervosa in Iran: Global Burden of Disease Study

Eating and Weight Disorders
Objectives Given the significant prevalence of mental health disorders in Iran, this research seeks to examine various epidemiological aspects related to eating disorders (ED).
Sohrab Amiri, Seyed Morteza Hosseini
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Analysis of covariance and sample size calculation for comparing means in randomized controlled trials [PDF]

Journal of Cardiovascular and Thoracic Research, 2023
Yousef Alimohamadi, Mojtaba Sepandi
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source