Results 211 to 220 of about 6,730,594 (397)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Improved long-term care provision in the context of population ageing. [PDF]
Chhetri JK +4 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Palliative care provision in motor neurone disease: A survey of multidisciplinary healthcare providers. [PDF]
Yoong J, Rees M.
europepmc +1 more source
Environmental and clinical ethics support decarbonising end-of-life care
Cristina Richie, Forbes McGain
openalex +1 more source
“It’s alright to ask for help”: findings from a qualitative study exploring the information and support needs of family carers at the end of life [PDF]
Emily Harrop +2 more
openalex +1 more source

