Results 251 to 260 of about 6,730,594 (397)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

"Cicely and David": Exploring the transformative power of theatre to communicate palliative care among university students. [PDF]

Palliat Care Soc Pract
Centeno I, Zapata C, Centeno C, Arantzamendi M.   +3 more
europepmc   +1 more source

The Advanced Trauma Life Support (ATLS®) Program in Trinidad and Tobago Positively Impacts Trauma Education and Care in the Caribbean

, 2018
Jameel Ali, Navin Sookar, Rasheed Adam, Henry Bedaysie, Ian Pierre, Sushilla Maharaj, Ernest Ali, Rosanna Robinson, Kenneth B. John, Grace Herrera Fernandez, Marsha Bedaysie   +10 more
openalex   +1 more source

The role of adult social care services in improving the quality of life of older carers and the individuals they support

Barbora Šilarova, Grace Collins, Stacey Rand, Alisoun Milne, Wenjing Zhang   +4 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Systems of care for cardiac arrest patients: Where are we going for tomorrow?

Resuscitation Plus
Kasper G. Lauridsen, Shir Lynn Lim
doaj   +1 more source

Withholding and withdrawing life support in critical care settings: ethical issues concerning consent

, 2007
Elisabeth Gedge, Mita Giacomini, Richard J. Cook   +2 more
openalex   +1 more source

Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Circulation, 2010
R. Berg, R. Hemphill, B. Abella, T. Aufderheide, Diana M. Cave, M. Fran, Hazinski, E. Lerner, T. Rea, M. Sayre, R. Swor, Berg Ra, H. R, Abella Bs, Aufderheide Tp, Dm Cave, Hazinski Mf, Lerner Eb, Rea Td, Sayre Mr, Swor Ra   +20 more
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Specialized Nursing-Led Interventions for Bladder Cancer Management: A Scoping Review of Evidence and Clinical Outcomes. [PDF]

Medicina (Kaunas)
Alqaisi O, Tai P, Storme G.
europepmc   +1 more source