Results 291 to 300 of about 6,730,594 (397)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Predicting tracheostomy in sepsis patients: an evaluation of the STeP score within the framework of future pandemics and cultural variations. [PDF]

J Intensive Care
Karanci Y.
europepmc   +1 more source

Basic life support training targeted to family members or carers of those at high-risk of out-of-hospital cardiac arrest: a systematic review

Zakary Doherty, Janet Bray, Judith Finn, Susie Cartledge   +3 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

"Incredibly Overwhelming": A Reflexive Thematic Analysis of the Psychological Impact of Venous Thromboembolism-A Patient-Oriented Study. [PDF]

J Patient Exp
Carrillo-Balam G, Lee T, Rajanderan T, Mackenzie T, Bonsu KO, Young S.   +5 more
europepmc   +1 more source

P-92 Engaging with domiciliary carers to enable improved support for people with frailty at end of life [PDF]

Paula Bavetta
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Prescriptions for Connection-Social Prescribing for Older People in Australia: Protocol for a Feasibility Study. [PDF]

Health Expect
Block H, Oster C, Dawson S, Gough C, Crawford GB, Boylan A, Angelo J, Freeman M, Milte R, Exley H, George S.   +10 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source