Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Life Table Parameters and Digestive Enzyme Activity of <i>Araecerus fasciculatus</i> (Coleoptera: Anthribidae) Feeding on Different Stored Products. [PDF]
Jian L +9 more
europepmc +1 more source
Life Table Parameters of Ceroplastes floridensis (Homoptera: Coccidae) at Different Temperatures
Nabil Abo Kaf, Iyad Mohammed, Ali Hasan
openaire +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Effects of three different host plants on two sex life table parameters of the fall armyworm Spodoptera frugiperda. [PDF]
Wang Z, Zhu H, Jin DC, Hou JT, Liu X.
europepmc +1 more source
Life Table Parameters of Tuta absoluta (Lepidoptera: Gelechiidae) On Six Tomato Cultivars
Gamila Selem +2 more
openaire +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
The Effects of Six <i>Brassica napus</i> Cultivars on the Life Table Parameters of the Green Peach Aphid <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae). [PDF]
Tian M, Li LK, Zhu F, Zhang SZ.
europepmc +1 more source
Comparison of Life Table Parameters and Digestive Physiology of Rhyzopertha dominica (Coleoptera: Bostrichidae) Fed on Various Barley Cultivars. [PDF]
Nemati-Kalkhoran M +3 more
europepmc +1 more source

