Results 121 to 130 of about 4,307,718 (307)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Metabolomics profiling of apples of different cultivars and growth locations

Food Innovation and Advances
Apple (Malus × domestica Borkh.) is a globally significant fruit in terms of both production and consumption. Metabolomics characteristics of 22 apple cultivars collected from five major apple-growing regions in Shanxi Province (China) were investigated ...
Kang Chen, Raghunath Pariyani, Yajing Li, Jindong Li, Xiongwu Qiao, Shu Qin, Baoru Yang   +6 more
doaj   +1 more source

Parameter Estimation in Step Stress Partially Accelerated Life Testing under Different Types of Censored Data. [PDF]

Comput Intell Neurosci, 2022
Kamal M, Siddiqui SA, Rahman A, Alsuhabi H, Alkhairy I, Barry TS.   +5 more
europepmc   +1 more source

Nickel-hydrogen cell low-Earth life test update [PDF]

When individual pressure vessel (IPV) nickel-hydrogen (Ni/H2) cells were selected as the energy storage system for the Space Station Freedom in March of 1986, a limited database existed on life and performance characteristics of these cells in a low ...
Frate, David T.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Low-Temperature Phosphine Fumigation Is Effective Against Drosophila suzukii in Sweet Cherry

Insects
Drosophila suzukii, classified as a quarantine pest in some countries, poses a serious threat to global trade due to its ability to damage berries and cherries.
Hang Zou, Li Li, Jun Zhang, Baishu Li, Yu Xiao, Yonglin Ren, Ju Huang, Wei Chen, Tao Liu   +8 more
doaj   +1 more source

College students' momentary stress and prescription drug misuse in daily life: Testing direct links and the moderating roles of global stress and coping. [PDF]

Stress Health, 2023
Papp LM, Kouros CD, Armstrong L, Curtin JJ.   +3 more
europepmc   +1 more source

A literature review on fatigue and creep interaction [PDF]

Life-time prediction methods, which are based on a number of empirical and phenomenological relationships, are presented. Three aspects are reviewed: effects of testing parameters on high temperature fatigue, life-time prediction, and high temperature ...
Chen, W. C.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Biopolymer Degradation Analysis: Accelerated Life Testing Study to Characterize Polylactic Acid Durability. [PDF]

Materials (Basel), 2021
Arias-Nava EH, Sullivan BP, Valles-Rosales DJ.   +2 more
europepmc   +1 more source