Results 151 to 160 of about 4,307,718 (307)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

NSPOMdb: a curated dataset of the objectionable microorganisms of non-sterile products

open access: yesScientific Data
Microbial contamination in non-sterile products (NSPs) presents significant risks to product quality and patient safety. While established regulatory standards delineate specific objectionable microorganisms (OMs), instances of product recalls have ...
Yanxiang Shen   +8 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The Testing of Life-jackets [PDF]

open access: yesOccupational and Environmental Medicine, 1957
R R, MACINTOSH, E A, PASK
openaire   +2 more sources

Do Non-Economic Quality of Life Factors Drive Immigration? [PDF]

open access: yes
This paper contributes to the immigration literature by generating two unique non-economic quality of life (QOL) indices and testing their role on recent migration patterns.
Lewer, Joshua J.   +2 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Estimation of oxidative indices in the raw and roasted hazelnuts by accelerated shelf-life testing. [PDF]

open access: yesJ Food Sci Technol, 2020
Shafiei G   +5 more
europepmc   +1 more source

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