Results 191 to 200 of about 1,469,069 (267)

Psychometric properties of Lehman's quality of life interview and its modifications: a systematic review using the COSMIN methodology. [PDF]

Schizophrenia (Heidelb)
Wiessner M, Le-Bert MZ, Wehr S, Weigel L, Leucht S.   +4 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Burden and distribution of serologically detected HIV and syphilis infections among pregnant women attending antenatal care in peri-urban Blantyre, Malawi. [PDF]

PLOS Glob Public Health
Kawonga N, Kaunda G, Machillika I, Chipojola R, Kawonga F.   +4 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Congenital Clitoromegaly With Concurrent Congenital Adrenal Hyperplasia and Turner Syndrome: A Case Report. [PDF]

Clin Med Insights Endocrinol Diabetes
Tisler A, Copenhaver EA, Naji GF, Menon S.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Apnea Testing for Brain Death/Death by Neurologic Criteria in Adults: A Prospective Multicenter Observational Study Assessing the Relationship Between Methodology, Safety, and Duration. [PDF]

Crit Care Explor
Cuninghame S, Basmaji J, Duffin J, Healey A, Paltser B, Snyder-Salehi M, Yoshiki A, Boyd JG, Hartwick M, Soliman K, Singh JM, Katz D, Beitel J, Ogunsakin E, Slessarev M.   +14 more
europepmc   +1 more source

A construction of statistical inferences in geographically weighted univariate log-gamma regression. [PDF]

MethodsX
Rini DS, Purhadi, Andari S.
europepmc   +1 more source

Point-of-care early infant HIV diagnosis at birth in a pragmatic cluster-randomized trial in Mozambique and Tanzania: A comparative cost and cost-effectiveness study. [PDF]

PLoS Med
Elsbernd K, Sabi I, Jani IV, Mudenyanga C, Boniface S, Mahumane A, Lequechane J, Chale F, Meggi B, Pereira K, Edom R, Lwilla AF, Buck WC, Ntinyinya NE, Hoelscher M, Baernighausen T, Kroidl A, Kohler S, Kohler S, LIFE Study Consortium.   +19 more
europepmc   +1 more source

Taste exposure during different developmental phases impacts aversion learning in adult rats. [PDF]

Behav Neurosci
Tanner B, Gemmell HM, Reifsnyder KC, Headley K, Maier JX, Flores VL.   +5 more
europepmc   +1 more source