Results 81 to 90 of about 1,462,566 (267)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Cultural Life: Theory and Empirical Testing
Biosystems, 2020 "What is life?" and Erwin Schrödinger's answer, "negative entropy", inspired researchers in the 20th century to unite physics, chemistry, and physiology into a new synthesis that many believe to be an important foundation for life science today.
openaire +5 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in ToxicologyTo study the ways in which compounds can induce adverse effects, toxicologists have been constructing Adverse Outcome Pathways (AOPs). An AOP can be considered as a pragmatic tool to capture and visualize mechanisms underlying different types of toxicity
Marie Corradi +9 more
doaj +1 more source
Better sleep, better life? testing the role of sleep on quality of life. [PDF]
PLoS One, 2023 Kudrnáčová M, Kudrnáč A.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Shipin gongye ke-jiThe extraction, isolation, purification, and structural characterization of proso millet bran polysaccharides (MBP), as well as its antibacterial activity were conducted to provide a reference for the development and utilization of nutrients in the ...
Yanyun CHEN +5 more
doaj +1 more source
Reliability assessment of transformer insulating oil using accelerated life testing. [PDF]
Sci Rep, 2022 Wei X, Wang Z, Guo J.
europepmc +1 more source
Storage Battery Life Tests: Part I . Laboratory Life Testing
Transactions of The Electrochemical Society, 1937 Two series of duplicate batteries were made. One series had a dense positive paste and the other series had a more voluminous positive paste. Identical negative plates were used with all of the batteries. These batteries were tested by ten different commercial battery manufacturers and their results were submitted for this final tabulation.
J. E. Hatfield, H. R. Harner
openaire +1 more source