Results 181 to 190 of about 6,630,500 (255)

Understanding the Pattern of Cognitive Decline in GBA1‐Related Parkinson's Disease: An Exploratory Longitudinal Multi‐Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective People with Parkinson's disease (PD) who carry a pathogenic GBA1 variant (PDGBA1) are at higher risk of cognitive impairment than those without the variant (PDGBA1_wildtype). To date, little is known about the pattern and evolution of cognitive decline in PDGBA1. This multicenter study characterized the cognitive profile of PDGBA, focusing on
Merle Bode   +345 more
wiley   +1 more source

Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology

open access: yesAnnals of Neurology, EarlyView.
Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko   +8 more
wiley   +1 more source

Accelerated Epigenetic Aging in Frontotemporal Dementia Highlights Smoking, Inflammation, and Metabolic Signals

open access: yesAnnals of Neurology, EarlyView.
Objective Epigenetic clocks are biomarkers of biological aging influenced by lifestyle and systemic factors. Accelerated epigenetic aging has been associated with neurodegeneration, but its relevance in frontotemporal dementia is unclear. We investigated biological aging in frontotemporal dementia using the GrimAge2 epigenetic clock, a DNA methylation ...
Daphne Nijland   +9 more
wiley   +1 more source

Brain outcomes with lifestyle change in adults with Down syndrome: Rationale and design for a 12-month randomized trial. [PDF]

open access: yesAlzheimers Dement
Ptomey LT   +15 more
europepmc   +1 more source

Physicochemical Characterization and Technological‐Functional Properties of Brazil Nut Flour and Protein Concentrate

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Representation of the graphical abstract of the investigation of physicochemical, functional, and technological properties and amino acid profile of partially defatted flour and protein concentrate from Brazil nuts. ABSTRACT It was investigated the physicochemical, functional and technological properties and amino acid profile of partially defatted ...
Ana Vânia Carvalho   +5 more
wiley   +1 more source

Experimental Studies on CO2 Hydrate Formation Kinetics With Kinetic Promoters

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Carbon dioxide (CO2) sequestration by means of gas hydrate formation is a promising method for mitigating global climate change. However, conventional surfactants like sodium dodecyl sulfate (SDS) exhibit limitations such as excessive foaming and environmental toxicity. This study examines the effectiveness and environmental impact of Tween 65
Anipeddi Manjusha, Bhajan Lal
wiley   +1 more source

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

open access: yesThe Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen   +3 more
wiley   +1 more source

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