Results 41 to 50 of about 6,630,500 (255)
The Behavioral and Clinical Effects of Therapeutic Lifestyle Change on Middle-aged Adults
Introduction Chronic diseases such as cancer, cardiovascular disease, stroke, and diabetes are responsible for most deaths in the United States. Lifestyle factors — poor nutrition, sedentary living, and tobacco use — appear to play a prominent role in ...
Steven G. Aldana, PhD +6 more
doaj
Living a successful weight loss after severe obesity
Purpose: Losing weight and keeping it off for the long term is difficult. Weight regain is common. Experiences of successful non-surgical weight loss after severe obesity are largely unexplored.
Eli Natvik +3 more
doaj +1 more source
Lifestyle, prevention, change & support : the views & attitudes of patients in Maltese family practice [PDF]
Introduction: General practitioners (GPs) are advised to consider their patients' views and attitudes in order to facilitate the success of preventive and health promotion interventions.
Sammut, Mario R.
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Metabolic-associated fatty liver disease (MAFLD) is the most common chronic liver disease observed in clinical practice worldwide. This disorder has been independently associated with an increased risk of developing chronic kidney disease (CKD).
Maria Magdalena Quetglas-Llabrés +9 more
doaj +1 more source
Hipertansiyona Pratik Yaklaşım
Hipertansiyon, önlenebilir ölüm nedenleri arasında ilk sırada yer almaktadır. Tedavi yetersizliğinde en önemli nokta, yaşam tarzı değişikliklerinin yeterince önemsenmemesi ve önerilmemesidir.
Yusuf Üstü, Mehmet Uğurlu
doaj +1 more source
Supporting Healthy Lifestyle Behavior Change in Hypertension Patients [PDF]
Hypertension is one of the most common health conditions and comorbidities, and is considered a silent killer. One of the non-pharmacological efforts to help hypertensive patients control their blood pressure is through changes in lifestyle to become ...
Santoso, Windu +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

