Results 91 to 100 of about 14,431,152 (338)

Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study

European Journal of Epidemiology, 2022
The risk factors for nonalcoholic fatty liver disease (NAFLD) have not been clearly identified. We conducted a Mendelian randomization (MR) study to explore this.
S. Yuan, Jie Chen, Xue Li, Rongrong Fan, B. Arsenault, D. Gill, E. Giovannucci, Junyi Zheng, S. Larsson   +8 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The Dynamic Interplay of Lifestyle, Dietary Factors, and Cardiometabolic Risk in Hypertension: A Cross-Sectional Investigation Among Saudi Adults

Diagnostics
Background/Objectives: Hypertension is a growing public health concern in Saudi Arabia, driven by rapid socioeconomic changes. This study investigated the interplay between habitual, behavioral, and dietary risk factors associated with hypertension among
Mohammad A. Jareebi
doaj   +1 more source

Prevalence and Correlates of Self-Reported Cardiovascular Diseases Among a Nationally Representative Population-Based Sample of Adults in Ecuador in 2018

Vascular Health and Risk Management, 2021
Supa Pengpid,1,2 Karl Peltzer3 1ASEAN Institute for Health Development, Mahidol University, Salaya, Nakhon Pathom, Thailand; 2Department of Research Administration and Development, University of Limpopo, Turfloop, South Africa; 3Department of Psychology,
Pengpid S, Peltzer K
doaj  

Prospective Study on the Association Between Adherence to Healthy Lifestyles and Depressive Symptoms Among Japanese Employees: The Furukawa Nutrition and Health Study

Journal of Epidemiology, 2020
Background: While a growing body of research suggests a protective role of healthy lifestyle against depression, evidence from prospective studies is scarce.
Ami Fukunaga, Yosuke Inoue, Takeshi Kochi, Huanhuan Hu, Masafumi Eguchi, Keisuke Kuwahara, Takako Miki, Kayo Kurotani, Akiko Nanri, Isamu Kabe, Tetsuya Mizoue   +10 more
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Exploring Chronic Pain, Immune Dysfunction and Lifestyle: A Focus on T Cell Exhaustion and Senescence

Biomolecules
Chronic pain conditions are debilitating and have an enormous impact on quality of life, yet underlying biological mechanisms remain poorly understood, hindering the development of diagnostic tools and effective treatments.
Yanthe Buntinx, Jolien Hendrix, Arne Wyns, Jente Van Campenhout, Huan-Yu Xiong, Thessa Laeremans, Sara Cuesta-Sancho, Joeri L. Aerts, Jo Nijs, Andrea Polli   +9 more
doaj   +1 more source

Lifestyle factors, self-management and patient empowerment in diabetes care

European Journal of Preventive Cardiology, 2019
Although management of diabetes mellitus is improving, inadequately managed cases still exist. Prevention of diabetes mellitus requires an integrated and holistic approach based on the origin of the disease. In Europe only half of diagnosed patients with
E. Lambrinou, T. Hansen, J. Beulens
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Secondary prevention of stroke: Using the experiences of patients and carers to inform the development of an educational resource [PDF]

, 2008
Copyright @ The Author 2008. This article is available open access through the publisher’s website at the link below.Background. Patients who have had one stroke are at increased risk of another.
Bak, Banet, C. Kilbride, Evans, J. L Campbell, Lopez, Mant, P. H Evans, R. Allison   +8 more
core   +1 more source