Results 181 to 190 of about 980,417 (331)

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence

Advanced Science, EarlyView.
Individual responses to food vary dramatically, challenging traditional dietary advice. This review explores how the unique genetic makeup, gut microbiome, and brain activity shape host metabolic health. We examine how artificial intelligence integrates these multimodal data to predict individualized dietary needs, moving beyond one‐size‐fits‐all ...
Yuanqing Fu, Ke Zhang, Zelei Miao, Gaoyi Yang, Yujing Huang, Ju‐Sheng Zheng   +5 more
wiley   +1 more source

Post‐Translational Modifications in Animal Circadian Clocks

Advanced Science, EarlyView.
Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley   +1 more source

ESTILO DE VIDA SALUDABLE EN LA PREVENCIÓN DE LA OSTEOPOROSIS EN LA MUJER CLIMATÉRICA

Revista Chilena de Obstetricia y Ginecología, 2007
Antecedentes: La osteoporosis es una enfermedad crónica no transmisible con factores de riesgo como sedentarismo, consumo de tabaco y alcohol, e ingesta de dieta no balaceada.
Ángelo González L, Victoria Espinosa F, Fanny López A, Lautaro Fernández M   +3 more
doaj  

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Bridging Scales in Flexible Perovskite Solar Cells: Mechanisms, Interfaces, and Applications

Advanced Science, EarlyView.
This perspective focuses on the advancement of flexible perovskite solar cells (f‐PSCs) from the energetic point of view, and summarizes the mechanisms, material characteristics, device performance, and failure mechanisms across the microscopic, mesoscopic, and macroscopic scales through mechanical energy dissipation theory.
Yan Wang, Zexin Yu, Chunlei Zhang, Ning Wang, Francesco Vanin, Bo Li, Nan Li, Meng Liao, Zonglong Zhu   +8 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Co-producing active lifestyles as whole-system-approach: theory, intervention and knowledge-to-action implications

Health Promotion International, 2019
A. Rütten, Annika Frahsa, T. Abel, Matthias Bergmann, E. de Leeuw, D. Hunter, Maria Jansen, A. King, L. Potvin   +8 more
semanticscholar   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source

Associations of lifestyles and frailty status with survival among older adults in China: a nationwide, community-based, prospective cohort study. [PDF]

BMC Geriatr
Ruan H, Ban C, Yi W, Yang L, Ma H, Zhao L, Wang Z, Wang K, Zheng Y, Song N, He S.   +10 more
europepmc   +1 more source